LoL-Starter requires you to have a current LoL-installation as it will just start the client just like you would.
This tiny program allows you to play on EU and US servers with just one single installation. You need to have the current lol client installed already (no matter which on, US or EU).
LoL-Starter is light weight and does not need to run after you started LoL with it. All it does is modifying your launcher.cfg, locale.cfg and system.cfg according to which server you want to connect to and the settings you selected. LoL-Starter is not required anymore once LoL has started.
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